However, researchers have issued a warning, stating that further investigation is necessary.
Sexually transmitted infections (STIs) are a significant public health concern in Canada, with rates of infections like chlamydia, gonorrhea, and syphilis rising in recent years.
Fortunately, Canada's healthcare system provides robust, confidential, and often free access to testing, treatment, and care.
The recommendations made by the Public Health Agency of Canada (PHAC) and the Canadian Guidelines on Sexually Transmitted Infections are the primary sources of inspiration for treatment guidelines in Canada. The following are basic treatments for sexually transmitted infections (STIs) caused by bacteria and parasites.
This guide provides an in-depth look at STI treatment in Canada, focusing on the standard medications used, how to access them, and the importance of completing prescribed therapies.
Canada operates on a system of universal publicly funded healthcare, meaning essential medical services are covered for Canadian citizens and permanent residents.
Each province and territory administers its own health insurance plan (e.g., OHIP in Ontario, MSP in British Columbia, RAMQ in Quebec).
The logic of the Canadian healthcare system for STIs is built on the principle of accessibility and confidentiality to curb epidemics. The key distinction is between the medical service and the pharmaceutical drug.
Medical Service (Testing and Procedures): Fully covered by the provincial public health insurance plan (e.g., OHIP in Ontario, MSP in BC). This includes:
Doctor's consultations.
Laboratory tests (blood, swabs, urine).
Any procedures performed in the clinic. This means an antibiotic injection (e.g., Ceftriaxone for gonorrhea or Penicillin G for syphilis) administered by a nurse under a doctor's orders will cost you nothing.
Pharmaceutical Drugs (Prescription Medications): Pills, creams, or suspensions that you get from a pharmacy with a prescription are typically not covered by the basic provincial health plan. Their cost is covered through:
Private insurance (from an employer or school).
Provincial drug benefit plans for specific groups (e.g., seniors, low-income individuals).
Out-of-pocket payment. Therefore, the cost of a course of doxycycline or azithromycin is usually paid by the patient if they lack private insurance.
Thus, the system aims to remove financial barriers at the diagnosis and critical treatment stage but shares the cost burden with the patient or their private insurer at the medication stage.
This protocol change (from dual therapy to monotherapy) is a direct response to the global threat of antimicrobial resistance.
The Reason: The bacterium Neisseria gonorrhoeae has demonstrated a frightening ability to develop resistance to antibiotics. The previous standard was a combination of Ceftriaxone (shot) and Azithromycin (pill). This was done to attack the bacteria with two different mechanisms, lowering the chance of resistant strains surviving.
The Problem: In recent years, resistance of gonorrhea to Azithromycin has surged worldwide, including in Canada. Using a drug that is losing effectiveness became not only pointless but dangerous: it promotes the selection of even more resistant superbugs.
The Solution: The Public Health Agency of Canada (PHAC) updated its guidelines, making a higher dose of Ceftriaxone (500 mg IM) the first-line treatment as monotherapy. This helps preserve its effectiveness by removing the failing component from the regimen. The final decision on the treatment protocol is always made by a physician based on the latest official guidelines and local resistance data.
This is a complex clinical situation that requires a specialized approach and supervision by an infectious disease specialist. Standard alternatives are not as reliable.
The Gold Standard - Desensitization: The most preferred option is penicillin desensitization. This procedure is performed in a hospital under close medical supervision. The patient is given gradually increasing doses of penicillin to "train" their immune system to tolerate it temporarily. After successful desensitization, a full course of Benzathine penicillin G injections can be administered safely. This is crucial as penicillin is the only truly reliable drug to cure syphilis, especially in its late stages and neurosyphilis.
Alternatives (with caveats): If desensitization is not possible, Doxycycline (100 mg orally twice daily for 14 days) may be considered for early syphilis only. However, this regimen:
Is not suitable for pregnant women.
Is not effective for treating late latent or tertiary syphilis, including neurosyphilis.
Requires even more rigorous and long-term serological follow-up after treatment.
Is considered less reliable than penicillin.
The decision is always made by a specialist, weighing the stage of the disease, risks, and the patient's circumstances.
Partner Notification is a confidential process vital for breaking the chain of STI transmission. It is typically handled in two main ways:
Patient Referral: A healthcare provider counsels the patient on how to inform their past partners themselves that they may have been exposed and should seek testing and treatment. They provide advice on how to do this anonymously.
Provider Referral: This is a more formal and anonymous process. The patient provides the contact information of their partners to a public health nurse. The nurse then contacts these individuals, informs them they have been exposed to an STI (without revealing the source patient's name), and strongly advises them to get tested and treated at a confidential clinic, often for free.
Its Importance: This practice breaks the chain of transmission. Treating one person is futile if their partners, who may be asymptomatic carriers, continue to spread the disease. It is a collective measure that protects not only individuals but also community health by slowing the rise of antibiotic resistance and overall infection rates.
The difference is fundamental and lies in the contrast between the concepts of "cure" and "management or control."
Bacterial Infections (Chlamydia, Gonorrhea, Syphilis):
Goal: Complete eradication of the pathogen from the patient's body.
Method: A short, targeted course of antibiotics (a single dose or a 1-2 week course). With correct treatment, the infection is completely and permanently cured.
Focus: A rapid and definitive solution.
Viral Infections (HIV, Herpes, HPV):
Goal: Suppression of the virus, control of its replication, and prevention of complications. Complete elimination of the virus is not yet possible with modern medicine.
Method: Long-term, often lifelong, suppressive therapy.
For HIV, this is a combination of antiretroviral drugs (ART) taken daily to reduce the viral load to an undetectable level.
For herpes, daily antiviral medication (e.g., valacyclovir) is used to suppress outbreaks and reduce transmission risk.
Focus: Transforming an incurable infection into a chronic but manageable condition, allowing for a full life and protecting partners (e.g., the U=U principle for HIV).